Do appointment systems work?

Appointment systems in general practice. Do patients like them, and how do they affect work load?

Adaptive Appointment Systems with Patient Preferences

P satisfaction with an appointment system when they attempt to book a nonurgent appointment is affected by their ability to book with a doctor of choice and to book an appointment at a convenient time of day. For medical conditions requiring urgent attention, patients want quick access to a familiar physician. For such instances, it is important for clinics to have open slots that allow same-da...

Mitigating Delays and Unfairness in Appointment Systems

We consider an appointment system where heterogeneous participants are sequenced and scheduled for service. As service times are uncertain, the aim is to mitigate the unpleasantness experienced by the participants in the system when their waiting times or delays exceed acceptable thresholds, and address fairness concerning balance of service levels among participants. In evaluating uncertain de...

How do CARs work?

Second-generation chimeric antigen receptors (CARs) are powerful tools to redirect antigen-specific T cells independently of HLA-restriction. Recent clinical studies evaluating CD19-targeted T cells in patients with B-cell malignancies demonstrate the potency of CAR-engineered T cells. With results from 28 subjects enrolled by five centers conducting studies in patients with chronic lymphocytic...

Do antidepressant medications work?

Treatment-resistant depression is extremely common-but does that mean there is no place for antidepressants?